For research use only. Not for therapeutic Use.
Halothane (CAT: A000083), commonly referred to as Fluothane, is a halogenated inhalation anesthetic widely used for induction and maintenance of general anesthesia. It acts as a volatile anesthetic by interacting with various neurotransmitter receptors, including gamma-aminobutyric acid (GABA) receptors, to induce a state of unconsciousness and pain relief during surgical procedures. Halothane is also recognized as a substrate for the cytochrome P450 enzyme CYP3A4, which plays a vital role in its metabolism and elimination from the body.
Catalog Number | A000083 |
CAS Number | 151-67-7 |
Synonyms | Narcotane |
Molecular Formula | C2HBrClF3 |
Purity | ≥95% |
Storage | -20°C |
InChI | 1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H |
InChIKey | BCQZXOMGPXTTIC-UHFFFAOYSA-N |
SMILES | C(C(F)(F)F)(Cl)Br |
Reference | 1: Chiba K, Wada T, Nakamura Y, Cao X, Hagiwara-Nagasawa M, Izumi-Nakaseko H, 2: Huang L, Sang CN, Desai MS. Beyond Ether and Chloroform-A Major Breakthrough <br> 4: Barkóczi B, Nagypál T, Nyujtó D, Katona X, Eördegh G, Bodosi B, Benedek G, 5: Cui XL, Wang YL, Tan G, Luo AL, Guo XY. Low-dose Simvastatin Increases 6: Bihani P, Choudhary D, Bhatia PK, Mohammed S. Halothane: I am still there. 7: Salas RC, Mingala CN. Genetic Factors Affecting Pork Quality: Halothane and 8: Jain N, Mathur PR, Khan S, Khare A, Mathur V, Sethi S. Effect of bispectral 9: Esser T, Keilhoff G, Ebmeyer U. Anesthesia specific differences in a 10: Cao X, Nakamura Y, Wada T, Izumi-Nakaseko H, Ando K, Sugiyama A. |