Harmaline

• CAT Number: R014730
• CAS Number: 304-21-2
• Molecular Formula: C13H14N2O
• Molecular Weight: 214.268
• Purity: ≥95%
• Synonyms: 4,9-dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
• Storage: -20°C
• IUPAC Name: 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
• InChI: InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,14H,5-6H2,1-2H3
• InChIKey: QJOZJXNKVMFAET-UHFFFAOYSA-N
• SMILES: CC1=C2C(=C3C=CC(=CC3=N2)OC)CCN1

Harmaline (Cat.No:R014730) is a naturally occurring beta-carboline alkaloid found in plants like Peganum harmala and Banisteriopsis caapi. It acts as a reversible inhibitor of monoamine oxidase enzymes and has been used in traditional medicine and shamanic rituals. It’s also studied for its potential psychoactive and medicinal properties.

Reference

1.Zheng XY, Zhang ZJ, Chou GX, Wu T, Cheng XM, Wang CH, Wang ZT. “Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay”. Arch Pharm Res. 2009 Sep;32(9):1245-51
2.M.J Schwarz, P.J Houghton, S Rose, P Jenner, A.D Lees, Activities of extract and constituents of Banisteriopsis caapi relevant to parkinsonism, Pharmacology Biochemistry and Behavior, Volume 75, Issue 3, June 2003, Pages 627-633
3.Shen HW, Jiang XL, Winter JC, Yu AM. Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions. Curr Drug Metab. 2010 Oct;11(8):659-66. Review