Haspin-IN-3

• CAT Number: I043832
• CAS Number: 2416569-95-2
• Molecular Formula: C16H10N2O3
• Molecular Weight: 278.26
• Purity: ≥95%
• Synonyms: (2Z)-6-hydroxy-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylidene)-1-benzofuran-3-one
• InChI: InChI=1S/C16H10N2O3/c19-10-3-4-12-13(7-10)21-14(15(12)20)6-9-8-18-16-11(9)2-1-5-17-16/h1-8,19H,(H,17,18)/b14-6-
• InChIKey: VHCZWXXMSGKCKC-NSIKDUERSA-N
• SMILES: C1=CC2=C(NC=C2C=C3C(=O)C4=C(O3)C=C(C=C4)O)N=C1

Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with IC50 of 14 nM. Haspin-IN-3 has anticancer effects[1].

Reference

[1]. Malikotsi A Qhobosheane, et al. Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors. Bioorg Med Chem. 2020 Jun 1;28(11):115468.
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