For research use only. Not for therapeutic Use.
hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].
hCAII-IN-8 (compound 9; 100 μM; 24-48 h) has noncytotoxic on HEK-293 T cells (cell viability>90%) compared to the control[1].
| Catalog Number | I042282 |
| CAS Number | 952306-80-8 |
| Synonyms | 3,4-dimethoxy-N-(3-sulfamoylphenyl)benzamide |
| Molecular Formula | C15H16N2O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C15H16N2O5S/c1-21-13-7-6-10(8-14(13)22-2)15(18)17-11-4-3-5-12(9-11)23(16,19)20/h3-9H,1-2H3,(H,17,18)(H2,16,19,20) |
| InChIKey | NXXHQVMWOQRKGC-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)N)OC |
| Reference | [1]. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264. |
