For research use only. Not for therapeutic Use.
HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells[1].
HDAC-IN-55(8j) acts on SW620 cell line and H520 cell line with the EC50 values of 4.47 and 1.61 μM, respectively[1].
HDAC-IN-55(8j) (10 μM, 24 h) can increase the expression of E-cadherin in SW620 cells and inhibit the proliferation of SW620 cells[1].
| Catalog Number | M088818 |
| CAS Number | 1268674-16-3 |
| Synonyms | 5-(furan-2-yl)-N-(4-pyridin-4-ylbutyl)-1,2-oxazole-3-carboxamide |
| Molecular Formula | C17H17N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H17N3O3/c21-17(14-12-16(23-20-14)15-5-3-11-22-15)19-8-2-1-4-13-6-9-18-10-7-13/h3,5-7,9-12H,1-2,4,8H2,(H,19,21) |
| InChIKey | HHXZAPLRXAUTOZ-UHFFFAOYSA-N |
| SMILES | C1=COC(=C1)C2=CC(=NO2)C(=O)NCCCCC3=CC=NC=C3 |
| Reference | [1]. Sydney L Stoops, et al. Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells. ACS Chem Biol. 2011 May 20;6(5):452-65. |
