HDAC6-IN-26

• CAT Number: I040513
• CAS Number: 2991427-19-9
• Molecular Formula: C13H12N8O
• Molecular Weight: 296.29
• Purity: ≥95%
• Synonyms: 6-[(5-pyridin-2-yltetrazol-2-yl)methyl]pyridine-3-carbohydrazide
• InChI: InChI=1S/C13H12N8O/c14-17-13(22)9-4-5-10(16-7-9)8-21-19-12(18-20-21)11-3-1-2-6-15-11/h1-7H,8,14H2,(H,17,22)
• InChIKey: IWWAKCDINOGSFB-UHFFFAOYSA-N
• SMILES: C1=CC=NC(=C1)C2=NN(N=N2)CC3=NC=C(C=C3)C(=O)NN

HDAC6-IN-26 (compound 23) is a potent inhibitor of HDAC6[1].

Reference

[1]. Ripa L et al. Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism. J Med Chem. 2023 Oct 26;66(20):14188-14207.
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