For research use only. Not for therapeutic Use.
hDHODH-IN-13 (compound w2) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 value of 173.4 nM. hDHODH-IN-13 can be used in the research of IBD[1].
| Catalog Number | I040308 |
| CAS Number | 3032611-13-2 |
| Synonyms | 2-[1-[(2-chloro-6-fluorophenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]-5-cyclopropylpyrimidin-4-amine |
| Molecular Formula | C21H17ClFN5 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H17ClFN5/c22-17-4-1-5-18(23)16(17)11-28-10-15(13-3-2-8-25-21(13)28)20-26-9-14(12-6-7-12)19(24)27-20/h1-5,8-10,12H,6-7,11H2,(H2,24,26,27) |
| InChIKey | ZESAVUVCFMDOPB-UHFFFAOYSA-N |
| SMILES | C1CC1C2=CN=C(N=C2N)C3=CN(C4=C3C=CC=N4)CC5=C(C=CC=C5Cl)F |
| Reference | [1]. Xia Zhou, et al. Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2023. |
