For research use only. Not for therapeutic Use.
HDM-201(CAT: I011408) is an orally bioavailable inhibitor of human double minute 2 homolog (HDM2). HDM2 is a protein that negatively regulates the tumor suppressor protein p53, which plays a critical role in cell cycle regulation and apoptosis. By inhibiting HDM2, HDM-201 has the potential to restore the activity of p53 and promote tumor cell death. As a result, HDM-201 shows promise as an antineoplastic agent for the treatment of cancer. Its oral bioavailability makes it a convenient option for administration. Ongoing research aims to further evaluate its efficacy and safety in clinical trials.
| Catalog Number | I011408 |
| CAS Number | 1448867-41-1 |
| Synonyms | (6S)-5-(5-Chloro-1,2-dihydro-1-methyl-2-oxo-3-pyridinyl)-6-(4-chlorophenyl)-2-(2,4-dimethoxy-5-pyrimidinyl)-5,6-dihydro-1-(1-methylethyl)pyrrolo[3,4-d]imidazol-4(1H)-one |
| Molecular Formula | C26 H24 Cl2 N6 O4 |
| Purity | ≥95% |
| Target | Metabolic Enzyme/Protease |
| Storage | -20°C |
| Reference | 1: PCT Int. Appl. (2013), WO 2013111105 A1 20130801. |
