For research use only. Not for therapeutic Use.
HDP 30.1699, the derivative of α-Amanitin, shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry[1][2].
Catalog Number | I044011 |
CAS Number | 2004724-36-9 |
Molecular Formula | C61H80N14O19S |
Purity | ≥95% |
Reference | [1]. Torsten HECHLER, et al. Amanitin antibody conjugates. WO2018115466A1. |