For research use only. Not for therapeutic Use.
Hematoporphyrin dihydrochloride (Cat No.: I007199) is a photosensitizer with notable biomedical applications. It serves as a substrate in hemopexin affinity chromatography techniques. Moreover, when activated by red light, Hematoporphyrin dihydrochloride induces apoptosis (programmed cell death) in U87 glioma cells. This light-activated apoptotic effect has also been observed to reduce tumor growth in vivo studies, highlighting its potential in photodynamic therapy for cancer treatment. Researchers are actively exploring the therapeutic applications of Hematoporphyrin dihydrochloride in the context of light-based cancer therapies and its interactions with target cells. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I007199 |
| CAS Number | 17696-69-4 |
| Synonyms | Hematoporphyrin HCl; Hematoporphyrin dihydrochloride; Hematoporphyrin HCl; Hematoporphyrin IX dihydrochloride; Photodyn, Sensibion.;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride |
| Molecular Formula | C34H40Cl2N4O6 |
| Purity | ≥95% |
| Target | Metabolic Enzyme/Protease |
| Solubility | Soluble in DMSO |
| Storage | Room Temperature |
| IUPAC Name | 3-[18-(2-carboxyethyl)-8,13-bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid;dihydrochloride |
| InChI | InChI=1S/C34H38N4O6.2ClH/c1-15-21(7-9-31(41)42)27-14-28-22(8-10-32(43)44)16(2)24(36-28)12-29-34(20(6)40)18(4)26(38-29)13-30-33(19(5)39)17(3)25(37-30)11-23(15)35-27;;/h11-14,19-20,37-40H,7-10H2,1-6H3,(H,41,42)(H,43,44);2*1H |
| InChIKey | WZQQOXSHARXAID-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)O.Cl.Cl |
| Reference | <br /> |
