For research use only. Not for therapeutic Use.
Hemiasterlin(CAT: I012578) is a highly potent natural tripeptide known for its antimitotic and anticancer properties. Originally isolated from marine sponges, Hemiasterlin disrupts microtubule dynamics by binding to tubulin, leading to the inhibition of cell division and the induction of apoptosis in cancer cells. Its unique mechanism of action, distinct from other microtubule-targeting agents like taxanes, makes Hemiasterlin a valuable compound in cancer research, particularly in the development of novel chemotherapeutic agents. Researchers focused on oncology, cell biology, and drug discovery use Hemiasterlin to investigate its therapeutic potential and to explore new strategies for targeting microtubules in cancer treatment.
| Catalog Number | I012578 |
| CAS Number | 157207-90-4 |
| Synonyms | (E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-(1-methylindol-3-yl)butanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid |
| Molecular Formula | C30H46N4O4 |
| Purity | ≥95% |
| IUPAC Name | (E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-(1-methylindol-3-yl)butanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid |
| InChI | InChI=1S/C30H46N4O4/c1-18(2)23(16-19(3)28(37)38)34(11)27(36)25(29(4,5)6)32-26(35)24(31-9)30(7,8)21-17-33(10)22-15-13-12-14-20(21)22/h12-18,23-25,31H,1-11H3,(H,32,35)(H,37,38)/b19-16+/t23-,24-,25-/m1/s1 |
| InChIKey | KQODQNJLJQHFQV-MKWZWQCGSA-N |
| SMILES | CC(C)C(C=C(C)C(=O)O)N(C)C(=O)C(C(C)(C)C)NC(=O)C(C(C)(C)C1=CN(C2=CC=CC=C21)C)NC |
