Heptelidic Acid (CAT: I012086) is a natural product derived from the fermentation of the fungus Verticillium sp. It possesses various pharmacological activities, including antifungal, antibacterial, and antitumor properties. Heptelidic Acid has been shown to inhibit the growth of several fungal and bacterial strains, making it a potential candidate for the development of new antimicrobial agents. Additionally, it has demonstrated cytotoxic effects against certain cancer cell lines, suggesting its potential as an antitumor agent. Further research is needed to fully elucidate the mechanisms of action and explore the therapeutic applications of Heptelidic Acid in various disease conditions.
Catalog Number | I012086 |
CAS Number | 57710-57-3 |
Synonyms | Koningic acid; Avocettin; FO-4443; BRN 5091359 |
Molecular Formula | C15H20O5 |
Purity | 95% |
Target | A potent and selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor |
Solubility | DMSO or EtOH |
Appearance | White solid |
Storage | -20°C |
Related CAS | Deleted CAS#: 74310-84-2 |
Analysis method | HPLC |
IUPAC Name | 1-oxo-6-propan-2-ylspiro[3,5a,6,7,8,9a-hexahydro-2-benzoxepine-9,2'-oxirane]-4-carboxylic acid |
InChI | InChI=1S/C15H20O5/c1-8(2)10-3-4-15(7-20-15)12-11(10)5-9(13(16)17)6-19-14(12)18/h5,8,10-12H,3-4,6-7H2,1-2H3,(H,16,17) |
InChIKey | JESMSCGUTIEROV-UHFFFAOYSA-N |
SMILES | CC(C)C1CCC2(CO2)C3C1C=C(COC3=O)C(=O)O |
Reference | <span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>1.ENDO, AKIRA, et al. "Specific inhibition of glyceraldehyde-3-phosphate dehydrogenase by koningic acid (heptelidic acid)." <i style=”font-family: Arial, sans-serif; font-size: 13px;”>The Journal of antibiotics</i> 38.7 (1985): 920-925.<br /> |