Hetrombopag Ethanolamine

• CAT Number: I007204
• CAS Number: 1257792-41-8
• Molecular Formula: C25H22N4O5
• Molecular Weight: 458.47
• Purity: ≥95%
• Synonyms: HetrombopagEthanolamine; SHR-8735; SHR8735; SHR 8735;(Z)-5-(2-hydroxy-3-(2-(3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)phenyl)furan-2-carboxylic acid
• Target: Thyroperoxidase Inhibitor
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term , or -20°C for long term.
• IUPAC Name: 5-[(5E)-5-[[5-methyl-3-oxo-2-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-4-yl]hydrazinylidene]-6-oxocyclohexa-1,3-dien-1-yl]furan-2-carboxylic acid
• InChI: InChI=1S/C25H22N4O5/c1-14-22(24(31)29(28-14)17-10-9-15-5-2-3-6-16(15)13-17)27-26-19-8-4-7-18(23(19)30)20-11-12-21(34-20)25(32)33/h4,7-13,27-28H,2-3,5-6H2,1H3,(H,32,33)/b26-19+
• InChIKey: ADOAYNSSNYWWAX-LGUFXXKBSA-N
• SMILES: CC1=C(C(=O)N(N1)C2=CC3=C(CCCC3)C=C2)NN=C4C=CC=C(C4=O)C5=CC=C(O5)C(=O)O

Hetrombopag Ethanolamine(CAT: I007204) is a small-molecule thrombopoietin receptor agonist (TPO-RA) designed to stimulate platelet production. It binds to the thrombopoietin receptor (MPL) on megakaryocytes and progenitor cells, promoting proliferation and differentiation, making it valuable in treating thrombocytopenia. The ethanolamine form enhances its solubility and bioavailability, ensuring effective research applications. Hetrombopag Ethanolamine is extensively used in hematological studies to investigate mechanisms of thrombopoiesis and potential therapeutic strategies for immune thrombocytopenia (ITP) and other platelet-related disorders. Its precision and efficacy provide researchers with an essential tool for advancing platelet biology and therapeutic innovation.