HEXADECENOIC ACID

• CAT Number: M078990
• CAS Number: 17004-51-2
• Molecular Formula: C16H30O2
• Molecular Weight: 254.41
• Purity: ≥95%
• Target: Bacterial
• Storage: Store at -20°C
• IUPAC Name: (Z)-hexadec-6-enoic acid
• InChI: InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h10-11H,2-9,12-15H2,1H3,(H,17,18)/b11-10-
• InChIKey: NNNVXFKZMRGJPM-KHPPLWFESA-N
• SMILES: CCCCCCCCC/C=C\CCCCC(=O)O

HEXADECENOIC ACID（Cat No.:M078990） is a naturally occurring fatty acid that is commonly found in the skin and mucous membranes. It exhibits variable antibacterial activity against both Gram-positive and Gram-negative bacteria typically found in the skin and oral cavity. HEXADECENOIC ACID is active against bacteria such as Streptococcus sanguinis, Streptococcus microbiota, and Clostridium nucleatum, with minimum bactericidal concentration (MBC) values of 31.3 μg/mL, 375.0 μg/mL, and 93.8 μg/mL, respectively. These properties suggest its potential role in the defense against bacterial infections in the skin and oral environment.

Reference

1. D. Downing et al. “Essential fatty acids and acne” Journal of the American Academy of Dermatology, Vol. 14:2 pp. 221-225, 19862. N. Nicolaides “Skin Lipids: Their Biochemical Uniqueness” Science, Vol. 186:4 pp. 19-26, 19743. L. Ge et al. “Identification of the ?-6 Desaturase of Human Sebaceous Glands: Expression and Enzyme Activity” Journal of Investigative Dermatology,Vol. 120 pp. 707-714, 20034. M. Ottaviani, E. Camera, and M. Picardo “Lipid Mediators in Acne” Mediators of Inflammation, Vol. 2010 pp. 1-6, 2010