Hexaethylene glycol phosphoramidite

• CAT Number: I028714
• CAS Number: 125607-09-2
• Molecular Formula: C36H57N2O10P
• Molecular Weight: 708.83
• Purity: 98%
• Synonyms: Hexaethylene glycol phosphoramidite
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1,1-bis(4-methoxyphenyl)-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite
• InChI: InChI=1S/C36H57N2O10P/c1-30(2)38(31(3)4)49(47-17-7-16-37)48-29-27-45-25-23-43-21-19-41-18-20-42-22-24-44-26-28-46-36(32-8-12-34(39-5)13-9-32)33-10-14-35(40-6)15-11-33/h8-15,30-31,36H,7,17-29H2,1-6H3
• InChIKey: UNSDQHBTBFNAIG-UHFFFAOYSA-N
• SMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCOCCOCCOC(C(C=C1)=CC=C1OC)C(C=C2)=CC=C2OC

Hexaethylene glycol phosphoramidite(CAT: I028714) is a versatile reagent widely used in oligonucleotide synthesis and molecular biology research. It facilitates the incorporation of polyethylene glycol (PEG) spacers into DNA or RNA sequences, enhancing solubility, reducing immunogenicity, and improving pharmacokinetic properties. This compound is particularly valuable for applications in therapeutic oligonucleotide development, probe design, and bioconjugation. Known for its high purity and stability, Hexaethylene glycol phosphoramidite supports precise and efficient modifications, enabling researchers to tailor nucleic acid structures for advanced biological studies and innovative drug development.