For research use only. Not for therapeutic Use.
Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.<br>Hexamethonium Bromide is effective against Ach and carbachol (CCh) on the amplitude of endplate responses of rat omohyoid muscle with EC50 of 300 μM and 100 μM, respectively. Hexamethonium Bromide (50-200 μM) causes an increase in the amplitude of nerve-evoked endplate currents (e.p.cs) recorded in the presence of 0.6 μM tubocurarine. Hexamethonium Bromide is also a weak inhibitor of acetylcholinesterase activity in rat muscle homogenates with EC50 of 1.5 mM.
| Catalog Number | A000731 |
| CAS Number | 55-97-0 |
| Synonyms | NA |
| Molecular Formula | C12H30N2.2Br |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Limited solubility |
| Storage | 3 years -20C powder |
