For research use only. Not for therapeutic Use.
Hexaminolevulinate hydrochloride (CAT: I001567) is a fluorescent agent utilized for the cystoscopic detection of papillary bladder cancer. It functions by inducing fluorescence in cancerous tissues, aiding in their visualization during cystoscopy procedures. This compound has been approved for clinical use to enhance the identification and diagnosis of papillary bladder cancer, thereby contributing to more accurate and effective medical interventions in the field of urology.
| Catalog Number | I001567 |
| CAS Number | 140898-91-5 |
| Molecular Formula | C11H22ClNO3 |
| Purity | ≥95% |
| Solubility | DMSO: ≥ 41 mg/mL |
| Storage | Store at -20°C |
| Reference | </br>1:Hexaminolevulinate hydrochloride blue-light flexible cystoscopy in the detection and follow-up of nonmuscle-invasive bladder cancer: cost consequences during outpatient surveillance in Sweden. Dansk V, Malmström PU, Bläckberg M, Malmenäs M.Future Oncol. 2016;12(8):1025-38. doi: 10.2217/fon-2015-0021. Epub 2016 Mar 15. PMID: 26975197 Free Article</br>2:Hexaminolevulinate hydrochloride in the detection of nonmuscle invasive cancer of the bladder. Di Stasi SM, De Carlo F, Pagliarulo V, Masedu F, Verri C, Celestino F, Riedl C.Ther Adv Urol. 2015 Dec;7(6):339-50. doi: 10.1177/1756287215603274. Review. PMID: 26622319 Free PMC Article</br>3:Budget impact of incorporating one instillation of hexaminolevulinate hydrochloride blue-light cytoscopy in transurethral bladder tumour resection for patients with non-muscle-invasive bladder cancer in Sweden. Rose JB, Armstrong S, Hermann GG, Kjellberg J, Malmström PU.BJU Int. 2016 Jun;117(6B):E102-13. doi: 10.1111/bju.13261. Epub 2015 Oct 29. PMID: 26305667 </br>4:The cost-effectiveness of blue light cystoscopy in bladder cancer detection: United States projections based on clinical data showing 4.5 years of follow up after a single hexaminolevulinate hydrochloride instillation. Garfield SS, Gavaghan MB, Armstrong SO, Jones JS.Can J Urol. 2013 Apr;20(2):6682-9. PMID: 23587507 Free Article</br>5:Is there a learning curve for photodynamic diagnosis of bladder cancer with hexaminolevulinate hydrochloride? Gravas S, Efstathiou K, Zachos I, Melekos MD, Tzortzis V.Can J Urol. 2012 Jun;19(3):6269-73. PMID: 22704312 |
