For research use only, not for therapeutic use.
Hexane-1,6-diyldiphosphonic acid(CAT: I016039) is a valuable alkyl chain-based linker commonly employed in the synthesis of PROTACs (PROteolysis TArgeting Chimeras). This molecule serves as a versatile bridge, enabling the precise connection of two different moieties in a PROTAC, such as a target-binding ligand and an E3 ligase ligand. The hexane-based linker provides the appropriate length and flexibility for maintaining optimal interactions between these components.
| Catalog Number | I016039 |
| CAS Number | 4721-22-6 |
| Molecular Formula | C₆H₁₆O₆P₂ |
| Purity | ≥95% |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
