For research use only. Not for therapeutic Use.
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
| Catalog Number | I028730 |
| CAS Number | 161258-30-6 |
| Synonyms | Hexapeptide-11; Peptamide 6; Fvapfp; Phe-val-ala-pro-phe-pro; |
| Molecular Formula | C36H48N6O7 |
| Purity | 98% |
| Target | Cell Cycle/DNA Damage |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline |
| InChI | InChI=1S/C36H48N6O7/c1-22(2)30(40-31(43)26(37)20-24-12-6-4-7-13-24)33(45)38-23(3)34(46)41-18-10-16-28(41)32(44)39-27(21-25-14-8-5-9-15-25)35(47)42-19-11-17-29(42)36(48)49/h4-9,12-15,22-23,26-30H,10-11,16-21,37H2,1-3H3,(H,38,45)(H,39,44)(H,40,43)(H,48,49)/t23-,26-,27-,28-,29-,30-/m0/s1 |
| InChIKey | GFEYWOGCSROPRT-OBXVVNIGSA-N |
| SMILES | O=C(O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)CCC3)=O)=O)CCC1 |
| Reference | 1: Sklirou AD, Ralli M, Dominguez M, Papassideri I, Skaltsounis AL, Trougakos IP. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 2015 Aug;5:205-15. doi: 10.1016/j.redox.2015.04.010. Epub 2015 Apr 29. PubMed PMID: 25974626; PubMed Central PMCID: PMC4434199. |
