Hexapeptide-11

• CAT Number: I028730
• CAS Number: 161258-30-6
• Molecular Formula: C36H48N6O7
• Molecular Weight: 676.81
• Purity: 98%
• Synonyms: Hexapeptide-11; Peptamide 6; Fvapfp; Phe-val-ala-pro-phe-pro
• Target: Cell Cycle/DNA Damage
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline
• InChI: InChI=1S/C36H48N6O7/c1-22(2)30(40-31(43)26(37)20-24-12-6-4-7-13-24)33(45)38-23(3)34(46)41-18-10-16-28(41)32(44)39-27(21-25-14-8-5-9-15-25)35(47)42-19-11-17-29(42)36(48)49/h4-9,12-15,22-23,26-30H,10-11,16-21,37H2,1-3H3,(H,38,45)(H,39,44)(H,40,43)(H,48,49)/t23-,26-,27-,28-,29-,30-/m0/s1
• InChIKey: GFEYWOGCSROPRT-OBXVVNIGSA-N
• SMILES: O=C(O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)CCC3)=O)=O)CCC1

Hexapeptide-11(CAT: I028730) is a novel modulator of the proteostasis network, widely studied in cellular and molecular biology research. It demonstrates the ability to regulate protein homeostasis in human diploid fibroblasts by influencing pathways involved in protein synthesis, folding, and degradation. This peptide is particularly valuable for investigating mechanisms of cellular aging, stress responses, and the maintenance of proteome integrity. Hexapeptide-11 provides insights into therapeutic strategies for age-related diseases, skin health, and degenerative conditions, making it a critical tool for advancing research into proteostasis and its impact on cellular function.