For research use only. Not for therapeutic Use.
Hexoprenaline sulfate (CAT: I007206) is a selective beta-2 adrenergic receptor agonist used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It acts by relaxing the smooth muscles in the airways, leading to bronchodilation and improved airflow. Hexoprenaline sulfate also exhibits some beta-1 adrenergic receptor agonist activity, which can have additional cardiovascular effects such as increased heart rate and contractility. It is typically administered via inhalation or oral route and has demonstrated efficacy in improving symptoms and lung function in patients with respiratory disorders.
| Catalog Number | I007206 |
| CAS Number | 32266-10-7 |
| Synonyms | Hexoprenaline Sulfate; Argocian; ST-1512; ST-1512; ST-1512; Gynipral;4,4/’-((hexane-1,6-diylbis(azanediyl))bis(1-hydroxyethane-2,1-diyl))bis(benzene-1,2-diol) sulfate |
| Molecular Formula | C22H34N2O10S |
| Purity | ≥95% |
| Target | Selective Beta2-Adrenoreceptor Agonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term , or -20°C for long term. |
| IUPAC Name | 4-[2-[6-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]hexylamino]-1-hydroxyethyl]benzene-1,2-diol;sulfuric acid |
| InChI | InChI=1S/C22H32N2O6.H2O4S/c25-17-7-5-15(11-19(17)27)21(29)13-23-9-3-1-2-4-10-24-14-22(30)16-6-8-18(26)20(28)12-16;1-5(2,3)4/h5-8,11-12,21-30H,1-4,9-10,13-14H2;(H2,1,2,3,4) |
| InChIKey | GTDCHGNGVGRHQY-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1C(CNCCCCCCNCC(C2=CC(=C(C=C2)O)O)O)O)O)O.OS(=O)(=O)O |
| Reference | 1:[Lesional pulmonary edema associated with tocolysis by hexoprenaline sulfate]. Rivier G, Nicole A, Stucki D, Regamey C.Schweiz Med Wochenschr. 1992 Feb 15;122(7):237-41. French. PMID: 1539126 <br /> |
