For research use only. Not for therapeutic Use.
HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor extracted from patent WO2015035223A1, Compound 232, has an IC50 of 16 nM in scintillation proximity assay (SPA)[1].
| Catalog Number | I046038 |
| CAS Number | 1672666-82-8 |
| Synonyms | 3-fluoro-5-[(2-fluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl)oxy]benzonitrile |
| Molecular Formula | C17H13F2NO4S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H13F2NO4S/c1-25(22,23)15-3-2-14(12-7-13(19)17(21)16(12)15)24-11-5-9(8-20)4-10(18)6-11/h2-6,13,17,21H,7H2,1H3 |
| InChIKey | GTHLUQQEKIJSME-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)C1=C2C(C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)F)O |
| Reference | [1]. Darryl David DIXON, et al. Aryl ethers and uses thereof. WO2015035223A1. |
