HIF-PHD-IN-3

• CAT Number: I041717
• CAS Number: 794582-71-1
• Molecular Formula: C16H13N3OS2
• Molecular Weight: 327.42
• Purity: ≥95%
• Synonyms: 2-phenylsulfanyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)acetamide
• InChI: InChI=1S/C16H13N3OS2/c20-15(11-21-12-6-2-1-3-7-12)19-16-18-14(10-22-16)13-8-4-5-9-17-13/h1-10H,11H2,(H,18,19,20)
• InChIKey: FEKFKURUDDXFPS-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)SCC(=O)NC2=NC(=CS2)C3=CC=CC=N3

HIF-PHD-IN-3 (compound 4) is a potent hiPSC-CM cardioprotective scaffold. HIF-PHD-IN-3 can induce upregulation of heme oxygenase-1[1].

Reference

[1]. Kirby RJ, et, al. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 Jan;364(1):87-96.
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