For research use only. Not for therapeutic Use.
Hikizimycin(Cat No.:M062597)is a nucleoside antibiotic produced by Streptomyces species, notable for its antifungal and antibacterial properties. It disrupts protein synthesis by inhibiting peptidyl transferase activity, making it effective against certain fungal pathogens and bacteria. In research, Hikizimycin is studied for its mechanism of action, particularly its role in blocking ribosomal function, which is crucial in microbial resistance studies. Its unique activity profile makes it a valuable tool for investigating new therapeutic avenues in infectious disease research, especially in the development of treatments targeting resistant microbial strains.
Catalog Number | M062597 |
CAS Number | 12706-94-4 |
Molecular Formula | C21H37N5O14 |
Purity | ≥95% |
Target | Bacterial |
Storage | Store at -20°C |
IUPAC Name | 4-amino-1-[(2R,3R,4S,5S,6S)-5-amino-6-[(1R,2S,3S,4R,5R)-1-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6-pentahydroxyhexyl]-3,4-dihydroxyoxan-2-yl]pyrimidin-2-one |
InChI | InChI=1S/C21H37N5O14/c22-7-1-2-26(21(37)25-7)19-16(36)12(32)9(24)17(39-19)18(15(35)14(34)10(30)5(29)3-27)40-20-13(33)8(23)11(31)6(4-28)38-20/h1-2,5-6,8-20,27-36H,3-4,23-24H2,(H2,22,25,37)/t5-,6-,8+,9+,10-,11-,12+,13-,14+,15+,16-,17+,18-,19-,20+/m1/s1 |
InChIKey | VQQSDVBOXQHCHU-SKPOXZENSA-N |
SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)[C@@H]([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N)O)O |