For research use only. Not for therapeutic Use.
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm[1].
HKOCl-3 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid[1].
HKOCl-3 (10 μM) shows a much higher increase in fluorescence intensity of compound HKOCl-3 than treatment with other ROS (10 μM) and RNS (100 μM) [1].
| Catalog Number | I045482 |
| CAS Number | 2031170-80-4 |
| Synonyms | 3′-(3,5-dichloro-4-hydroxyphenoxy)-6′-hydroxyspiro[2-benzofuran-3,9′-xanthene]-1-one |
| Molecular Formula | C26H14Cl2O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H14Cl2O6/c27-20-10-15(11-21(28)24(20)30)32-14-6-8-19-23(12-14)33-22-9-13(29)5-7-18(22)26(19)17-4-2-1-3-16(17)25(31)34-26/h1-12,29-30H |
| InChIKey | OWWYBZBGVRLHND-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)OC6=CC(=C(C(=C6)Cl)O)Cl |
| Reference | [1]. Dan Yang, et al. Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical. Patent US20160312033. |
