HLY78

• CAT Number: I011840
• CAS Number: 854847-61-3
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.33
• Purity: ≥95%
• Synonyms: 4-ethyl-5,6-dihydro-5-methyl-[1,3]-dioxolo[4,5-j] phenanthridine
• Target: Apoptosis
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 4-ethyl-5-methyl-6H-[1,3]dioxolo[4,5-j]phenanthridine
• InChI: InChI=1S/C17H17NO2/c1-3-11-5-4-6-13-14-8-16-15(19-10-20-16)7-12(14)9-18(2)17(11)13/h4-8H,3,9-10H2,1-2H3
• InChIKey: FAZZYPIBZBGQSH-UHFFFAOYSA-N
• SMILES: CCC1=C2C(=CC=C1)C3=CC4=C(C=C3CN2C)OCO4

HLY78（Cat No.:I011840）is a small molecule compound studied for its potential in cancer therapy, particularly in targeting the protein Bcl-2, which plays a key role in regulating apoptosis (programmed cell death). HLY78 is known to inhibit Bcl-2 and other members of the Bcl-2 family of proteins, thereby promoting the death of cancer cells that have developed resistance to apoptosis. Preclinical studies have shown promise in its ability to enhance the effectiveness of existing cancer treatments by sensitizing tumor cells. Ongoing research is focused on evaluating HLY78’s safety, efficacy, and clinical applications in oncology.