HMN-154

• CAT Number: I013394
• CAS Number: 173528-92-2
• Molecular Formula: C₂₀H₁₈N₂O₃S
• Molecular Weight: 366.43
• Purity: ≥95%
• Target: Others
• Solubility: DMSO: ≥15 mg/mL
• IUPAC Name: 4-methoxy-N-[2-[(E)-2-pyridin-4-ylethenyl]phenyl]benzenesulfonamide
• InChI: InChI=1S/C20H18N2O3S/c1-25-18-8-10-19(11-9-18)26(23,24)22-20-5-3-2-4-17(20)7-6-16-12-14-21-15-13-16/h2-15,22H,1H3/b7-6+
• InChIKey: CIJCDFMGZYKSSC-VOTSOKGWSA-N
• SMILES: COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C=CC3=CC=NC=C3

HMN-154(CAT: I013394) is a novel benzenesulfonamide compound that has shown potential as an anticancer agent. It has been found to inhibit the growth of KB cells (human cervical cancer cells) and colon38 cells (colon cancer cells) in preclinical studies. HMN-154 likely exerts its anticancer effects through specific mechanisms that affect cell proliferation, survival, or other processes crucial for tumor growth. Further research is needed to fully understand its mode of action and its potential as a therapeutic agent in cancer treatment.

Reference

[1]. Tanaka H, et al. Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. Mol Pharmacol. 1999 Feb;55(2):356-63.