HO-PEG20-OH

• CAT Number: I016572
• CAS Number: 351342-08-0
• Molecular Formula: C₄₀H₈₂O₂₁
• Molecular Weight: 899.07
• Purity: ≥95%
• Target: PROTAC Linkers
• IUPAC Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
• InChI: 1S/C40H82O21/c41-1-3-43-5-7-45-9-11-47-13-15-49-17-19-51-21-23-53-25-27-55-29-31-57-33-35-59-37-39-61-40-38-60-36-34-58-32-30-56-28-26-54-24-22-52-20-18-50-16-14-48-12-10-46-8-6-44-4-2-42/h41-42H,1-40H2
• InChIKey: ZHMUMDLGQBRJIW-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)O

HO-PEG20-OH(Cat No.: I016572), or hydroxyl-terminated polyethylene glycol (PEG) with a molecular weight of approximately 20 kDa, is a biocompatible and hydrophilic polymer widely used in biomedical and pharmaceutical applications. It serves as a key component in drug delivery systems, protein stabilization, and surface modifications to enhance biocompatibility. HO-PEG20-OH is commonly utilized in PEGylation to improve drug solubility, circulation time, and reduce immunogenicity. Additionally, it is employed in hydrogels, nanocarriers, and biomaterials for tissue engineering and controlled drug release applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562