HOE-316

• CAT Number: I028833
• CAS Number: 54093-05-9
• Molecular Formula: C14H18N10O4
• Molecular Weight: 390.36
• Purity: 98%
• Synonyms: HOE316; HOE 316; HOE-316
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (E)-1-(1-methyl-5-nitroimidazol-2-yl)-N-[4-[(E)-(1-methyl-5-nitroimidazol-2-yl)methylideneamino]piperazin-1-yl]methanimine
• InChI: InChI=1S/C14H18N10O4/c1-19-11(15-9-13(19)23(25)26)7-17-21-3-5-22(6-4-21)18-8-12-16-10-14(20(12)2)24(27)28/h7-10H,3-6H2,1-2H3/b17-7+,18-8+
• InChIKey: VAQAPFZZUCFMRC-ZEELXFFVSA-N
• SMILES: CN1C(=NC=C1[N+](=O)[O-])/C=N/N2CCN(CC2)/N=C/C3=NC=C(N3C)[N+](=O)[O-]

HOE-316（Cat No.:I028833）is a synthetic compound that functions as a potent antagonist of the angiotensin II type 1 (AT1) receptor, involved in regulating blood pressure and fluid balance. By blocking the binding of angiotensin II to its receptor, HOE-316 helps to prevent vasoconstriction, which reduces blood pressure and alleviates symptoms related to hypertension and cardiovascular diseases. It has been studied for its potential therapeutic role in conditions such as hypertension, heart failure, and kidney disease. Research on HOE-316 continues, focusing on its efficacy, safety profile, and possible applications in treating cardiovascular disorders.