Hoechst 33258 analog 5

• CAT Number: I002782
• CAS Number: 23491-55-6
• Molecular Formula: C29H26N6
• Molecular Weight: 458.56
• Purity: ≥95%
• Synonyms: 6-(4-methylpiperazin-1-yl)-2/’-(naphthalen-2-yl)-1H,3/’H-2,5/’-bibenzo[d]imidazole
• Target: DNA Stain
• Solubility: DMSO or water Protect from light
• Storage: Store at -20°C

Hoechst 33258 analog 5 (CAT: I002782) is a derivative or analog of Hoechst 33258, a fluorescent dye widely used in molecular biology and cell biology research. Like its parent compound, Hoechst 33258 analog 5 is commonly utilized as a DNA stain. It selectively binds to the minor groove of double-stranded DNA, resulting in a fluorescent complex that can be visualized under appropriate microscopy or fluorescence detection methods. This property makes it valuable for various applications, including DNA visualization, chromatin analysis, cell cycle studies, and DNA quantification. The analog retains the key characteristics of Hoechst 33258, offering researchers an alternative fluorescent probe for DNA-related investigations.

Reference

[1]. Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505.
[2]. a b c /Hoechst Stains/. Invitrogren (Molecular Probes).
[3]. Portugal J, Waring MJ. Assignment of DNA binding sites for 4/’,6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68.