Homo-PROTAC pVHL30 degrader 1

• CAT Number: I019410
• CAS Number: 2244684-49-7
• Molecular Formula: C₅₈H₈₂N₈O₁₄S₂
• Molecular Weight: 1179.45
• Purity: ≥95%
• Target: PROTACs

Homo-PROTAC pVHL30 degrader 1(CAT: I019410) represents an innovative approach in the field of targeted protein degradation through PROTAC (PROteolysis TArgeting Chimeras) technology. This compound is designed to specifically degrade pVHL30, offering a novel strategy to modulate the levels of this protein. By employing a homo-PROTAC mechanism, Homo-PROTAC pVHL30 degrader 1 leverages the principles of PROTACs to induce the ubiquitination-mediated degradation of pVHL30.

Reference

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.