Homogentisic Acid-13C6

• CAT Number: R012116
• CAS Number: 1216468-48-2
• Molecular Formula: C8H8O4
• Molecular Weight: 174.102
• Purity: ≥95%
• Synonyms: 2,5-Dihydroxybenzeneacetic Acid-13C6; 2,5-Dihydroxy-α-toluic Acid-13C6; 2,5-Dihydroxyphenylacetic Acid-13C6; Alcapton-13C6; Homogentisinic Acid-13C6; NSC 88940-13C6
• Storage: -20°C
• IUPAC Name: 2-(2,5-dihydroxyphenyl)acetic acid
• InChI: InChI=1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)/i1+1,2+1,3+1,5+1,6+1,7+1
• InChIKey: IGMNYECMUMZDDF-JTZKEMBVSA-N
• SMILES: [13CH]1=[13CH][13C](=[13C]([13CH]=[13C]1O)CC(=O)O)O

Homogentisic Acid-13C6 is an isotopically labeled form of homogentisic acid, a key intermediate in the catabolic pathway of tyrosine and phenylalanine. This compound is labeled with six carbon-13 atoms, which enhances its stability and allows for precise tracking in metabolic studies and isotope-labeled experiments. Homogentisic Acid-13C6 is particularly valuable in research focused on metabolic disorders, such as alkaptonuria, where homogentisic acid accumulation is a key pathological feature. It is also used in isotope-dilution mass spectrometry for accurate quantification and as a tracer in metabolic pathway studies. This high-purity, isotopically labeled compound is essential for obtaining reliable and reproducible results in biochemical and clinical research, particularly in studies of amino acid metabolism and related disorders.