For research use only. Not for therapeutic Use.
HPGDS Inhibitor 1(CAT: I000204) is a potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS), an enzyme involved in the production of prostaglandin D2 (PGD2). This compound is widely used in research investigating inflammatory and allergic diseases, as well as the role of PGD2 in immune modulation and mast cell activity. By targeting HPGDS, it provides insights into the regulation of prostaglandin pathways and their therapeutic potential. Its high specificity and stability ensure reliable experimental outcomes, making HPGDS Inhibitor 1 a valuable tool for advancing studies in immunology, inflammation, and drug discovery.
| Catalog Number | I000204 |
| CAS Number | 1033836-12-2 |
| Synonyms | 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyridine-3-carboxamide |
| Molecular Formula | C19H19F4N3O |
| Purity | ≥95% |
| Target | PGE synthase |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20C |
| IC50 | 0.7 nM [1] |
| IUPAC Name | 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyridine-3-carboxamide |
| InChI | InChI=1S/C19H19F4N3O/c20-15-3-1-2-13(10-15)17-5-4-14(11-24-17)18(27)25-16-6-8-26(9-7-16)12-19(21,22)23/h1-5,10-11,16H,6-9,12H2,(H,25,27) |
| InChIKey | LPUCBGGXXIUBAZ-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=C(C2=CC=CC(F)=C2)N=C1)NC3CCN(CC(F)(F)F)CC3 |
