HPN 16663

• CAT Number: I028873
• CAS Number: 58816-66-3
• Molecular Formula: C11H15ClN2O4
• Molecular Weight: 274.70
• Purity: 98%
• Synonyms: Ethyl 4-nitro-L-phenylalanine (hydrochloride); HPN 16663; HPN-16663; HPN16663
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: ethyl (S)-2-amino-3-(4-nitrophenyl)propanoate hydrochloride
• InChI: InChI=1S/C11H14N2O4.ClH/c1-2-17-11(14)10(12)7-8-3-5-9(6-4-8)13(15)16;/h3-6,10H,2,7,12H2,1H3;1H/t10-;/m0./s1
• InChIKey: HHZUMTWHYNIFOC-PPHPATTJSA-N
• SMILES: O=C([C@H](CC1=CC=C(C=C1)[N+]([O-])=O)N)OCC.Cl

HPN 16663(CAT: I028873), also known as Ethyl 4-nitro-L-phenylalanine, is a versatile chemical building block used in the synthesis of bioactive compounds. Its structure, featuring a nitro group on the phenyl ring, allows for further chemical modifications, making it valuable in drug discovery and medicinal chemistry. HPN 16663 has been specifically utilized in the development of chemokine receptor 3 (CCR3) antagonists, which are explored for treating inflammatory and allergic diseases, and α4β1 integrin antagonists, which are investigated for their potential in managing autoimmune disorders and cancer metastasis. It serves as a key intermediate for creating targeted therapeutic agents.