HSD-016

For research use only. Not for therapeutic Use.

  • CAT Number: I028900
  • CAS Number: 946396-92-5
  • Molecular Formula: C21H21F7N2O3S
  • Molecular Weight: 514.46
  • Purity: ≥95%
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HSD-016(Cat No.:I028900)is an investigational compound that acts as a selective inhibitor of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1), an enzyme involved in the conversion of estrone to estradiol, a potent estrogen. By inhibiting this enzyme, HSD-016 aims to lower estrogen levels, which could be beneficial in the treatment of estrogen-dependent conditions such as hormone receptor-positive breast cancer. Additionally, it may have potential applications in other diseases related to estrogen overproduction. HSD-016 is being studied for its ability to selectively target this pathway, offering a potential therapeutic option for managing estrogen-related disorders.


CAS Number 946396-92-5
Synonyms

(2R)-1,1,1-trifluoro-2-[3-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylphenyl]propan-2-ol

Molecular Formula C21H21F7N2O3S
Purity ≥95%
IUPAC Name (2R)-1,1,1-trifluoro-2-[3-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylphenyl]propan-2-ol
InChI InChI=1S/C21H21F7N2O3S/c1-13-12-29(18-7-6-15(22)11-17(18)20(23,24)25)8-9-30(13)34(32,33)16-5-3-4-14(10-16)19(2,31)21(26,27)28/h3-7,10-11,13,31H,8-9,12H2,1-2H3/t13-,19-/m1/s1
InChIKey ZWASRJHIEFYJGL-BFUOFWGJSA-N
SMILES C[C@@H]1CN(CCN1S(=O)(=O)C2=CC=CC(=C2)[C@](C)(C(F)(F)F)O)C3=C(C=C(C=C3)F)C(F)(F)F
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