For research use only. Not for therapeutic Use.
Human heat shock factor protein (HSF1) activator; close analogue of HSF1A (Axon 1890).
KEYWORDS: HSF1B | 1196723-95-1 | Axon 2101 | HSF1 inhibitor | Axon Ligands | Axon Medchem | Supplier | Axon2101 | HSF1 | Heat shock factor protein | neurodegenerative | Huntington’s | poly-glutamine | polyQ
Catalog Number | I047593 |
CAS Number | 1196723-95-1 |
Molecular Formula | C26H23Cl2N3O |
Purity | ≥95% |
IUPAC Name | N-[2,5-bis(4-chlorophenyl)pyrazol-3-yl]-4-butylbenzamide |
InChI | InChI=1S/C26H23Cl2N3O/c1-2-3-4-18-5-7-20(8-6-18)26(32)29-25-17-24(19-9-11-21(27)12-10-19)30-31(25)23-15-13-22(28)14-16-23/h5-17H,2-4H2,1H3,(H,29,32) |
SMILES | CCCCC1=CC=C(C=C1)C(=O)NC2=CC(=NN2C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl |
Reference | DW Neef, ML Turski, DJ Thiele. Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease. PLoS Biol. 2010, 8(1), e1000291. |