Hsp90-IN-17 hydrochloride

• CAT Number: I042644
• CAS Number: 1253584-63-2
• Molecular Formula: C21H21ClN4O7
• Molecular Weight: 476.87
• Purity: ≥95%
• Synonyms: 5-[2,4-dihydroxy-6-(4-nitrophenoxy)phenyl]-N-piperidin-4-yl-1,2-oxazole-3-carboxamide;hydrochloride
• InChI: InChI=1S/C21H20N4O7.ClH/c26-14-9-17(27)20(18(10-14)31-15-3-1-13(2-4-15)25(29)30)19-11-16(24-32-19)21(28)23-12-5-7-22-8-6-12;/h1-4,9-12,22,26-27H,5-8H2,(H,23,28);1H
• InChIKey: KYYNVXMTLPAYQC-UHFFFAOYSA-N
• SMILES: C1CNCCC1NC(=O)C2=NOC(=C2)C3=C(C=C(C=C3OC4=CC=C(C=C4)[N+](=O)[O-])O)O.Cl

Hsp90-IN-17 hydrochloride（Cat No.:I042644）is a small molecule inhibitor that targets heat shock protein 90 (Hsp90), a molecular chaperone involved in the stabilization and activation of various client proteins, including many oncogenic proteins. By inhibiting Hsp90, Hsp90-IN-17 disrupts the proper folding and function of these client proteins, leading to their degradation. This action has significant therapeutic potential in cancer, where Hsp90 supports the function of multiple proteins critical for tumor growth and survival. Research is ongoing to evaluate its efficacy and safety in preclinical and clinical settings, especially for cancer treatment.