HTH-01-091

• CAT Number: I028919
• CAS Number: 2000209-42-5
• Molecular Formula: C26H28Cl2N4O2
• Molecular Weight: 499.43
• Purity: ≥95%
• Synonyms: 9-(3,5-dichloro-4-hydroxyphenyl)-1-[4-[(dimethylamino)methyl]cyclohexyl]-3,4-dihydropyrimido[5,4-c]quinolin-2-one
• InChI: InChI=1S/C26H28Cl2N4O2/c1-31(2)14-15-3-6-19(7-4-15)32-24-18(13-30-26(32)34)12-29-23-8-5-16(9-20(23)24)17-10-21(27)25(33)22(28)11-17/h5,8-12,15,19,33H,3-4,6-7,13-14H2,1-2H3,(H,30,34)
• InChIKey: FUVRHGKKWNNBJX-UHFFFAOYSA-N
• SMILES: CN(C)CC1CCC(CC1)N2C3=C4C=C(C=CC4=NC=C3CNC2=O)C5=CC(=C(C(=C5)Cl)O)Cl

HTH-01-091（Cat No.:I028919）is a small molecule compound under investigation for its potential use in treating psychiatric and neurological disorders. It acts as a selective antagonist of the 5-HT6 receptor, a serotonin receptor implicated in cognitive function, mood regulation, and neurodegenerative diseases. By blocking this receptor, HTH-01-091 aims to enhance cognitive function and improve memory in conditions like Alzheimer’s disease and schizophrenia. Preclinical studies suggest that it may offer therapeutic benefits by modulating serotonin pathways, potentially providing a novel approach to treating cognitive decline and other disorders related to serotonin dysregulation.