human GIP(3-30), amide TFA

• CAT Number: I040204
• Molecular Formula: C150H226N38O44S.xC2HF3O2
• Molecular Weight: 3297.69 (free base)
• Purity: ≥95%

Human GIP(3-30), amide TFA (Cat No.:  I040204)  is a peptide fragment derived from the glucagon-like peptide-1 (GLP-1) receptor, specifically the truncated form of gastric inhibitory polypeptide (GIP). It functions as an antagonist to the GIP receptor, inhibiting the effects of GIP on insulin secretion and glucose homeostasis. This compound is often used in research to investigate the role of GIP in metabolic disorders such as diabetes and obesity. By blocking GIP signaling, it provides insights into potential therapeutic approaches for metabolic diseases.

Reference

[1]. Sparre-Ulrich AH, et al. GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release. Biochem Pharmacol. 2017;131:78-88.
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