Human IgG1 (F405L) kappa, Isotype Control

• CAT Number: I040965
• Purity: ≥95%

Human IgG1 (F405L) kappa, Isotype Control (Cat No.: I040965) is a recombinant monoclonal antibody featuring an F405L Fc mutation that reduces Fc receptor binding, minimizing effector functions. It is used as a negative control in immunoassays to distinguish non-specific binding from antigen-specific activity. The kappa light chain configuration and IgG1 backbone ensure compatibility with human immune system models. This isotype control is essential for validating antibody specificity in flow cytometry, ELISA, and in vivo studies. For research use only in controlled experiments.