For research use only. Not for therapeutic Use.
Human IgG4 (S228P) Kappa, Isotype Control(CAT: I040969) is a non-targeting monoclonal antibody engineered as a negative control for immunological assays. It features an S228P mutation in the hinge region, which enhances stability and minimizes Fab arm exchange, ensuring consistent antibody behavior. With an IgG4 subclass and kappa (κ) light chain, it provides structural similarity to test antibodies while lacking antigen specificity. This control helps distinguish non-specific background effects from true antigen-antibody interactions in flow cytometry, ELISA, Western blot, and in vivo studies. Given its role in immune response studies, it is most relevant to Inflammation & Immunology Research, particularly in immunotherapy development and immune modulation research.
| Catalog Number | I040969 |
| Purity | ≥95% |
