HUN 66673

• CAT Number: I028934
• CAS Number: 2169266-67-3
• Molecular Formula: C18H18N2O7
• Molecular Weight: 374.349
• Purity: 98%
• Synonyms: Thalidomide 4'-ether-alkylC4-acid; Thalidomide 4' ether alkylC4 acid; HUN 66673; HUN-66673; HUN66673
• Target: Autophagy
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)pentanoic acid
• InChI: InChI=1S/C18H18N2O7/c21-13-8-7-11(16(24)19-13)20-17(25)10-4-3-5-12(15(10)18(20)26)27-9-2-1-6-14(22)23/h3-5,11H,1-2,6-9H2,(H,22,23)(H,19,21,24)
• InChIKey: HCUNNTIALPNNPY-UHFFFAOYSA-N
• SMILES: OC(CCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O)=O

HUN 66673 is a chemical compound known for its role as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4), which is involved in the regulation of intracellular levels of cyclic AMP. Its chemical structure facilitates its activity in modulating inflammatory responses and is of interest in research for potential therapeutic applications, particularly in treating respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD). HUN 66673 represents a valuable tool in pharmacological studies focused on anti-inflammatory effects.