Hydrocortisone sodium succinate

• CAT Number: R055362
• CAS Number: 125-04-2
• Molecular Formula: C25H33O8.Na
• Molecular Weight: 484.51
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: [Na+].CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)COC(=O)CCC([O-])=O)C4(C)CC(O)C23

Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.

Reference

[1] B S Kang, et al. Biol Pharm Bull. 2001 Jun;24(6):701-3.