Hydroxy-PEG2-C2-PFP ester

• CAT Number: I016987
• CAS Number: 1820673-42-4
• Molecular Formula: C13H13F5O5
• Molecular Weight: 344.23
• Purity: ≥95%
• Synonyms: (2,3,4,5,6-pentafluorophenyl) 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
• InChI: InChI=1S/C13H13F5O5/c14-8-9(15)11(17)13(12(18)10(8)16)23-7(20)1-3-21-5-6-22-4-2-19/h19H,1-6H2
• InChIKey: FTFZBMSTIHCECX-UHFFFAOYSA-N
• SMILES: C(COCCOCCO)C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F

Hydroxy-PEG2-C2-PFP ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.