For research use only. Not for therapeutic Use.
Hydroxy-PEG3-acid (CAT: I015297) is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTAC molecules. PROTACs (PROteolysis TArgeting Chimeras) are innovative compounds designed to harness the ubiquitin-proteasome system for targeted protein degradation. The hydroxy-PEG3-acid linker is strategically designed to connect the binding components of the PROTAC, facilitating the interaction with the target protein and promoting its subsequent degradation by the cellular machinery.
| Catalog Number | I015297 |
| CAS Number | 518044-49-0 |
| Molecular Formula | C₉H₁₈O₆ |
| Purity | ≥95% |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
