For research use only. Not for therapeutic Use.
Hydroxy-PEG4-methylamine (CAT: I016092) is a PEG-based linker compound specifically designed for use in the synthesis of PROTACs (Proteolysis-Targeting Chimeras). It consists of a polyethylene glycol (PEG) backbone with a hydroxy group and a terminal methylamine functional group. This linker is utilized to conjugate target-specific ligands with E3 ligase ligands, enabling the formation of PROTAC molecules. PROTACs are innovative molecules that exploit the body’s own proteasomal degradation system to selectively eliminate disease-causing proteins.
| Catalog Number | I016092 |
| CAS Number | 90430-59-4 |
| Molecular Formula | C₉H₂₁NO₄ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
