For research use only. Not for therapeutic Use.
Hydroxy-PEG6-Boc (CAT: I016590) represents a versatile PEG-based PROTAC linker, strategically engineered for use in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). With its hydroxy-terminated polyethylene glycol (PEG) backbone and Boc (tert-butyloxycarbonyl) protecting group, this linker offers a tailored platform for the construction of novel molecular entities. Integrating this linker into PROTAC design, it enables precise conjugation of target-specific ligands and E3 ligase-recruiting moieties, facilitating the targeted degradation of disease-associated proteins.
| Catalog Number | I016590 |
| CAS Number | 361189-64-2 |
| Molecular Formula | C₁₉H₃₈O₉ |
| Purity | ≥95% |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
