For research use only. Not for therapeutic Use.
Hydroxy-PEG9-Boc(CAT: I016589) stands as a polyethylene glycol (PEG) derivative commonly employed as a linker in the construction of PROTAC molecules. By incorporating this linker into the design of PROTACs, it facilitates the targeted degradation of specific proteins within cells. The hydroxy functionality provides a point for attachment and the Boc protecting group ensures stability during synthesis.
Catalog Number | I016589 |
CAS Number | 2055042-66-3 |
Molecular Formula | C₂₅H₅₀O₁₂ |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |