Hydroxy Pioglitazone-D5 (Major) (M-IV)(Mixture of Diastereomers)

• CAT Number: R007018
• CAS Number: 1189445-29-1
• Molecular Formula: C19H20N2O4S
• Molecular Weight: 377.47
• Purity: ≥95%
• Synonyms: 5-[[4-[2-[5-(1-Hydroxyethyl-d4)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione-D5
• Storage: -20°C
• IUPAC Name: 5-deuterio-5-[[4-[2-[5-(1,2,2,2-tetradeuterio-1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
• InChI: InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11-12,17,22H,8-10H2,1H3,(H,21,23,24)/i1D3,12D,17D
• InChIKey: OXVFDZYQLGRLCD-ARVCVUNTSA-N
• SMILES: [2H]C1(C(=O)NC(=O)S1)CC2=CC=C(C=C2)OCCC3=NC=C(C=C3)C([2H])(C([2H])([2H])[2H])O

Hydroxy Pioglitazone-D5 (Major) (M-IV)(Mixture of Diastereomers)（Cat No.:R007018） is a deuterated form of hydroxy pioglitazone, featuring five deuterium atoms. This isotopic enhancement significantly aids in the pharmacokinetic and metabolic profiling of pioglitazone, a medication used primarily in diabetes management. As a mixture of diastereomers, it provides insight into the drug’s metabolic diversity and its various biological effects. Utilized in mass spectrometry and NMR spectroscopy, this compound helps researchers accurately trace and quantify metabolic products, facilitating the development of safer and more effective therapeutic regimens for diabetes treatment.