For research use only. Not for therapeutic Use.
Hydroxychloroquine Sulfate(Cat No.:A000121)is a widely used antimalarial and immunomodulatory drug. It works by interfering with parasite lysosomal activity and pH, effectively treating Plasmodium infections. Beyond malaria, it is commonly prescribed for autoimmune conditions such as rheumatoid arthritis and systemic lupus erythematosus, where it modulates immune responses by inhibiting antigen processing and cytokine production. Hydroxychloroquine Sulfate has also been investigated for antiviral activity in certain infections. Known for its oral bioavailability and long-term safety, it remains a cornerstone treatment for various inflammatory and parasitic diseases.
Catalog Number | A000121 |
CAS Number | 747-36-4 |
Synonyms | NA |
Molecular Formula | C18H26ClN3O ? H2SO4 |
Purity | ≥95% |
Target | Immunology/Inflammation |
Storage | -20°C |
IUPAC Name | 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid |
InChI | InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4) |
InChIKey | JCBIVZZPXRZKTI-UHFFFAOYSA-N |
SMILES | CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O |
Reference | 1: McHenry AR, Wempe MF, Rice PJ. Stability of Extemporaneously Prepared 2: Fan HW, Ma ZX, Chen J, Yang XY, Cheng JL, Li YB. Pharmacokinetics and 3: Chen FY, Xue B, Wang H. [Analysis of the clinical efficacy of yiqi fumai 4: Liu YM, Chen Q, Zhang MQ, Liu GY, Jia JY, Pu HH, Liu Y, Hu CY, Lu C, Wang W, 5: Chopra A, Saluja M, Tillu G, Venugopalan A, Narsimulu G, Handa R, Bichile L, <br> 7: James JA, Kim-Howard XR, Bruner BF, Jonsson MK, McClain MT, Arbuckle MR, 8: Eisen D. Hydroxychloroquine sulfate (Plaquenil) improves oral lichen planus: 9: Bernstein HN. Ocular safety of hydroxychloroquine sulfate (Plaquenil). South 10: Canadian Hydroxychloroquine Study Group. A randomized study of the effect of |