Hydroxyhexamide

• CAT Number: I000038
• CAS Number: 3168-01-2
• Molecular Formula: C15H22N2O4S
• Molecular Weight: 326.41
• Purity: ≥95%
• Target: Drug Metabolite
• Solubility: 10 mM in DMSO
• Storage: -20°C
• IUPAC Name: 1-cyclohexyl-3-[4-(1-hydroxyethyl)phenyl]sulfonylurea
• InChI: InChI=1S/C15H22N2O4S/c1-11(18)12-7-9-14(10-8-12)22(20,21)17-15(19)16-13-5-3-2-4-6-13/h7-11,13,18H,2-6H2,1H3,(H2,16,17,19)
• InChIKey: VQDAEOYLIBGCHE-UHFFFAOYSA-N
• SMILES: CC(C1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)O

Hydroxyhexamide(CAT: I000038) is a derivative of the sulfonylurea class of compounds, structurally related to hexamide, known for its role in modulating insulin secretion. Sulfonylureas function by stimulating insulin release from pancreatic β-cells through the inhibition of ATP-sensitive potassium (K⁺) channels, leading to cell depolarization and subsequent insulin secretion. Hydroxyhexamide is primarily utilized in metabolic disease research, particularly in studying the mechanisms of type 2 diabetes mellitus (T2DM) and pancreatic β-cell function. Its structure allows researchers to explore potential therapeutic targets for enhancing insulin sensitivity and developing advanced treatments for diabetes and metabolic disorders.